6 selections by the Buffalo Sabres in the 2019 NHL Entry Draft.
| Year | Pick | Round | Team | Player | Pos | Amateur Club | League | Country |
|---|---|---|---|---|---|---|---|---|
| 2019 | 7 | 1 | Buffalo Sabres | Dylan Cozens | C | Lethbridge | WHL | CAN |
| 2019 | 31 | 1 | Buffalo Sabres | Ryan Johnson | D | Sioux Falls | USHL | USA |
| 2019 | 67 | 3 | Buffalo Sabres | Erik Portillo | G | Frolunda Jr. | SWEDEN-JR. | SWE |
| 2019 | 102 | 4 | Buffalo Sabres | Aaron Huglen | RW | Roseau | HIGH-MN | USA |
| 2019 | 143 | 5 | Buffalo Sabres | Filip Cederqvist | LW | Vaxjo | SWEDEN | SWE |
| 2019 | 160 | 6 | Buffalo Sabres | Lukas Rousek | RW | Sparta | CZREP | CZE |