6 selections by the Pittsburgh Penguins in the 2016 NHL Entry Draft.
| Year | Pick | Round | Team | Player | Pos | Amateur Club | League | Country |
|---|---|---|---|---|---|---|---|---|
| 2016 | 55 | 2 | Pittsburgh Penguins | Filip Gustavsson | G | Lulea Jr. | SWEDEN-JR. | SWE |
| 2016 | 61 | 2 | Pittsburgh Penguins | Kasper Bjorkqvist | RW | Blues Jr. | Finland Jr. | FIN |
| 2016 | 77 | 3 | Pittsburgh Penguins | Connor Hall | D | Kitchener | OHL | CAN |
| 2016 | 121 | 4 | Pittsburgh Penguins | Ryan Jones | D | Lincoln | USHL | USA |
| 2016 | 151 | 5 | Pittsburgh Penguins | Niclas Almari | D | Jokerit Jr. | Finland Jr. | FIN |
| 2016 | 181 | 6 | Pittsburgh Penguins | Joseph Masonius | D | U. of Connecticut | H-EAST | USA |