12 selections by the Pittsburgh Penguins in the 2004 NHL Entry Draft.
| Year | Pick | Round | Team | Player | Pos | Amateur Club | League | Country |
|---|---|---|---|---|---|---|---|---|
| 2004 | 2 | 1 | Pittsburgh Penguins | Evgeni Malkin | F | Magnitogorsk | RUS | RUS |
| 2004 | 31 | 2 | Pittsburgh Penguins | Johannes Salmonsson | F | Djurgarden | SWEDEN | SWE |
| 2004 | 61 | 2 | Pittsburgh Penguins | Alex Goligoski | D | Sioux Falls | USHL | USA |
| 2004 | 67 | 3 | Pittsburgh Penguins | Nick Johnson | RW | St. Albert | AJHL | CAN |
| 2004 | 85 | 3 | Pittsburgh Penguins | Brian Gifford | C | Moorhead | USHSW | USA |
| 2004 | 99 | 4 | Pittsburgh Penguins | Tyler Kennedy | C | Sault Ste. Marie | OHL | CAN |
| 2004 | 130 | 5 | Pittsburgh Penguins | Michal Sersen | D | Rimouski | QMJHL | SVK |
| 2004 | 164 | 6 | Pittsburgh Penguins | Moises Gutierrez | RW | Kamloops | WHL | USA |
| 2004 | 194 | 7 | Pittsburgh Penguins | Chris Peluso | D | Brainerd H.S. | USHSW | USA |
| 2004 | 222 | 7 | Pittsburgh Penguins | Jordan Morrison | C | Peterborough | OHL | CAN |
| 2004 | 228 | 8 | Pittsburgh Penguins | David Brown | G | U. of Notre Dame | CCHA | CAN |
| 2004 | 259 | 9 | Pittsburgh Penguins | Brian Ihnacak | C | Brown U. | ECAC | CAN |