6 selections by the Ottawa Senators in the 2025 NHL Entry Draft.
| Year | Pick | Round | Team | Player | Pos | Amateur Club | League | Country |
|---|---|---|---|---|---|---|---|---|
| 2025 | 23 | 1 | Ottawa Senators | Logan Hensler | D | Wisconsin | BIG10 | USA |
| 2025 | 93 | 3 | Ottawa Senators | Blake Vanek | RW | Stillwater | HIGH-MN | USA |
| 2025 | 97 | 4 | Ottawa Senators | Lucas Beckman | G | Baie Comeau | QMJHL | CAN |
| 2025 | 149 | 5 | Ottawa Senators | Dmitri Isayev | LW | Yekaterinburg Jr. | RUSSIA-JR. | RUS |
| 2025 | 181 | 6 | Ottawa Senators | Bruno Idzan | LW | Lincoln | USHL | HRV |
| 2025 | 213 | 7 | Ottawa Senators | Andrei Trofimov | G | Magnitogorsk Jr. | RUSSIA-JR. | RUS |