8 selections by the Ottawa Senators in the 2005 NHL Entry Draft.
| Year | Pick | Round | Team | Player | Pos | Amateur Club | League | Country |
|---|---|---|---|---|---|---|---|---|
| 2005 | 9 | 1 | Ottawa Senators | Brian Lee | D | Moorhead | USHSW | USA |
| 2005 | 70 | 3 | Ottawa Senators | Vitaly Anikeyenko | D | Yaroslavl 2 | RUSSIA-3 | RUS |
| 2005 | 95 | 4 | Ottawa Senators | Cody Bass | C | Mississauga | OHL | CAN |
| 2005 | 98 | 4 | Ottawa Senators | Ilya Zubov | C | Chelyabinsk | RUSSIA-2 | RUS |
| 2005 | 115 | 4 | Ottawa Senators | Janne Kolehmainen | LW | Saipa | FINLAND | FIN |
| 2005 | 136 | 5 | Ottawa Senators | Tomas Kudelka | D | Zlin Jr. | CZE JR. | CZE |
| 2005 | 186 | 6 | Ottawa Senators | Dimitri Megalinsky | D | Yaroslavl | RUS | RUS |
| 2005 | 204 | 7 | Ottawa Senators | Colin Greening | F | Upper Canada Coll. | CCL | CAN |