8 selections by the Ottawa Senators in the 2018 NHL Entry Draft.
| Year | Pick | Round | Team | Player | Pos | Amateur Club | League | Country |
|---|---|---|---|---|---|---|---|---|
| 2018 | 4 | 1 | Ottawa Senators | Brady Tkachuk | LW | Boston University | H-EAST | USA |
| 2018 | 26 | 1 | Ottawa Senators | Jacob Bernard-Docker | D | Okotoks | AJHL | CAN |
| 2018 | 48 | 2 | Ottawa Senators | Jonathan Tychonick | D | Penticton | BCHL | CAN |
| 2018 | 95 | 4 | Ottawa Senators | Jonathan Gruden | C | U.S. National Team | NTDP | USA |
| 2018 | 126 | 5 | Ottawa Senators | Angus Crookshank | LW | Langley | BCHL | CAN |
| 2018 | 157 | 6 | Ottawa Senators | Kevin Mandolese | G | Cape Breton | QMJHL | CAN |
| 2018 | 188 | 7 | Ottawa Senators | Jakov Novak | LW | Janesville | NAHL | CAN |
| 2018 | 194 | 7 | Ottawa Senators | Luke Loheit | RW | Minnetonka | HIGH-MN | USA |