4 selections by the Ottawa Senators in the 2010 NHL Entry Draft.
| Year | Pick | Round | Team | Player | Pos | Amateur Club | League | Country |
|---|---|---|---|---|---|---|---|---|
| 2010 | 76 | 3 | Ottawa Senators | Jakub Culek | LW | Rimouski | QMJHL | CZE |
| 2010 | 106 | 4 | Ottawa Senators | Marcus Sorensen | RW | Sodertalje Jr. | SWEDEN-JR. | SWE |
| 2010 | 178 | 6 | Ottawa Senators | Mark Stone | RW | Brandon | WHL | CAN |
| 2010 | 196 | 7 | Ottawa Senators | Bryce Aneloski | D | Cedar Rapids | USHL | USA |