7 selections by the Ottawa Senators in the 2006 NHL Entry Draft.
| Year | Pick | Round | Team | Player | Pos | Amateur Club | League | Country |
|---|---|---|---|---|---|---|---|---|
| 2006 | 28 | 1 | Ottawa Senators | Nick Foligno | LW | Sudbury | OHL | USA |
| 2006 | 68 | 3 | Ottawa Senators | Eric Gryba | D | Green Bay | USHL | CAN |
| 2006 | 91 | 3 | Ottawa Senators | Kaspars Daugavins | LW | Riga | LAT | LVA |
| 2006 | 121 | 4 | Ottawa Senators | Pierre-Luc Lessard | D | Gatineau | QMJHL | CAN |
| 2006 | 151 | 5 | Ottawa Senators | Ryan Daniels | G | Saginaw | OHL | CAN |
| 2006 | 181 | 6 | Ottawa Senators | Kevin Koopman | D | Beaver Valley Jr. B | KIJHL | CAN |
| 2006 | 211 | 7 | Ottawa Senators | Erik Condra | RW | U. of Notre Dame | CCHA | USA |