5 selections by the Toronto Maple Leafs in the 2022 NHL Entry Draft.
| Year | Pick | Round | Team | Player | Pos | Amateur Club | League | Country |
|---|---|---|---|---|---|---|---|---|
| 2022 | 38 | 2 | Toronto Maple Leafs | Fraser Minten | C | Kamloops | WHL | CAN |
| 2022 | 95 | 3 | Toronto Maple Leafs | Nicholas Moldenhauer | RW | Chicago | USHL | CAN |
| 2022 | 122 | 4 | Toronto Maple Leafs | Dennis Hildeby | G | Farjestad Jr. | SWEDEN-JR. | SWE |
| 2022 | 135 | 5 | Toronto Maple Leafs | Nikita Grebenkin | RW | Magnitogorsk 2 | RUSSIA-JR. | RUS |
| 2022 | 218 | 7 | Toronto Maple Leafs | Brandon Lisowsky | LW | Saskatoon | WHL | CAN |