12 selections by the Toronto Maple Leafs in the 2001 NHL Entry Draft.
| Year | Pick | Round | Team | Player | Pos | Amateur Club | League | Country |
|---|---|---|---|---|---|---|---|---|
| 2001 | 17 | 1 | Toronto Maple Leafs | Carlo Colaiacovo | D | Erie | OHL | CAN |
| 2001 | 39 | 2 | Toronto Maple Leafs | Karel Pilar | D | Litvinov | CZE | CZE |
| 2001 | 65 | 3 | Toronto Maple Leafs | Brendan Bell | D | Ottawa | OHL | CAN |
| 2001 | 82 | 3 | Toronto Maple Leafs | Jay Harrison | D | Brampton | OHL | CAN |
| 2001 | 88 | 3 | Toronto Maple Leafs | Nicolas Corbeil | C | Sherbrooke | QMJHL | CAN |
| 2001 | 134 | 5 | Toronto Maple Leafs | Kyle Wellwood | C | Belleville | OHL | CAN |
| 2001 | 168 | 6 | Toronto Maple Leafs | Maxim Kondratiev | D | Togliatti Jr. | RUS | RUS |
| 2001 | 183 | 6 | Toronto Maple Leafs | Jaroslav Sklenar | F | Brno | CZE JR. | CZE |
| 2001 | 198 | 7 | Toronto Maple Leafs | Ivan Kolozvary | F | Trencin Jr. | SVK | SVK |
| 2001 | 213 | 7 | Toronto Maple Leafs | Jan Chovan | G | Belleville | OHL | SVK |
| 2001 | 246 | 8 | Toronto Maple Leafs | Tomas Mojzis | D | Moose Jaw | WHL | CZE |
| 2001 | 276 | 9 | Toronto Maple Leafs | Mike Knoepfli | LW | Georgetown | OPJA | CAN |