7 selections by the Toronto Maple Leafs in the 2006 NHL Entry Draft.
| Year | Pick | Round | Team | Player | Pos | Amateur Club | League | Country |
|---|---|---|---|---|---|---|---|---|
| 2006 | 13 | 1 | Toronto Maple Leafs | Jiri Tlusty | F | Kladno | CZE | CZE |
| 2006 | 44 | 2 | Toronto Maple Leafs | Nikolay Kulemin | F | Magnitogorsk | RUS | RUS |
| 2006 | 99 | 4 | Toronto Maple Leafs | James Reimer | G | Red Deer | WHL | CAN |
| 2006 | 111 | 4 | Toronto Maple Leafs | Korbinian Holzer | D | Bad Tolz | GERMANY | DEU |
| 2006 | 161 | 6 | Toronto Maple Leafs | Viktor Stalberg | LW | Frolunda | SWEDEN | SWE |
| 2006 | 166 | 6 | Toronto Maple Leafs | Tyler Ruegsegger | F | Shattuck-St. Mary's | USHSW | USA |
| 2006 | 180 | 6 | Toronto Maple Leafs | Leo Komarov | C | Assat | FINLAND | EST |