6 selections by the St. Louis Blues in the 2022 NHL Entry Draft.
| Year | Pick | Round | Team | Player | Pos | Amateur Club | League | Country |
|---|---|---|---|---|---|---|---|---|
| 2022 | 23 | 1 | St. Louis Blues | Jimmy Snuggerud | RW | USA U-18 | NTDP | USA |
| 2022 | 73 | 3 | St. Louis Blues | Aleksanteri Kaskimaki | C | HIFK Jr. | FINLAND-JR. | FIN |
| 2022 | 88 | 3 | St. Louis Blues | Michael Buchinger | D | Guelph | OHL | CAN |
| 2022 | 120 | 4 | St. Louis Blues | Arseni Koromyslov | D | SKA St. Petersburg 2 | RUSSIA-JR. | RUS |
| 2022 | 152 | 5 | St. Louis Blues | Marc-Andre Gaudet | D | Acadie-Bathurst | QMJHL | CAN |
| 2022 | 184 | 6 | St. Louis Blues | Landon Sim | RW | London | OHL | CAN |