10 selections by the St. Louis Blues in the 2008 NHL Entry Draft.
| Year | Pick | Round | Team | Player | Pos | Amateur Club | League | Country |
|---|---|---|---|---|---|---|---|---|
| 2008 | 4 | 1 | St. Louis Blues | Alex Pietrangelo | D | Niagara | OHL | CAN |
| 2008 | 33 | 2 | St. Louis Blues | Philip McRae | C | London | OHL | USA |
| 2008 | 34 | 2 | St. Louis Blues | Jake Allen | G | St. John's | QMJHL | CAN |
| 2008 | 65 | 3 | St. Louis Blues | Jori Lehtera | C | Tappara | FINLAND | FIN |
| 2008 | 70 | 3 | St. Louis Blues | James Livingston | RW | Sault Ste. Marie | OHL | CAN |
| 2008 | 87 | 3 | St. Louis Blues | Ian Schultz | RW | Calgary | WHL | CAN |
| 2008 | 95 | 4 | St. Louis Blues | David Warsofsky | D | USA U-18 | USDP | USA |
| 2008 | 125 | 5 | St. Louis Blues | Kristoffer Berglund | D | Bjorkloven | SWEDEN-2 | SWE |
| 2008 | 155 | 6 | St. Louis Blues | Anthony Nigro | C | Guelph | OHL | CAN |
| 2008 | 185 | 7 | St. Louis Blues | Paul Karpowich | G | Wellington | OPJHL | CAN |