6 selections by the St. Louis Blues in the 2018 NHL Entry Draft.
| Year | Pick | Round | Team | Player | Pos | Amateur Club | League | Country |
|---|---|---|---|---|---|---|---|---|
| 2018 | 25 | 1 | St. Louis Blues | Dominik Bokk | RW | Vaxjo Jr. | SWEDEN-JR. | DEU |
| 2018 | 45 | 2 | St. Louis Blues | Scott Perunovich | D | Minnesota-Duluth | NCHC | USA |
| 2018 | 107 | 4 | St. Louis Blues | Joel Hofer | G | Swift Current | WHL | CAN |
| 2018 | 138 | 5 | St. Louis Blues | Hugh McGing | LW | Western Michigan | NCHC | USA |
| 2018 | 169 | 6 | St. Louis Blues | Mathias Laferriere | RW | Cape Breton | QMJHL | CAN |
| 2018 | 200 | 7 | St. Louis Blues | Tyler Tucker | D | Barrie | OHL | CAN |