8 selections by the St. Louis Blues in the 2016 NHL Entry Draft.
| Year | Pick | Round | Team | Player | Pos | Amateur Club | League | Country |
|---|---|---|---|---|---|---|---|---|
| 2016 | 26 | 1 | St. Louis Blues | Tage Thompson | C | U. of Connecticut | H-EAST | USA |
| 2016 | 35 | 2 | St. Louis Blues | Jordan Kyrou | C | Sarnia | OHL | CAN |
| 2016 | 59 | 2 | St. Louis Blues | Evan Fitzpatrick | G | Sherbrooke | QMJHL | CAN |
| 2016 | 119 | 4 | St. Louis Blues | Tanner Kaspick | C | Brandon | WHL | CAN |
| 2016 | 125 | 5 | St. Louis Blues | Nolan Stevens | C | Northeastern U. | H-EAST | CAN |
| 2016 | 144 | 5 | St. Louis Blues | Conner Bleackley | C | Red Deer | WHL | CAN |
| 2016 | 209 | 7 | St. Louis Blues | Nikolaj Krag Christensen | C/LW | Rodovre | DENMARK | DNK |
| 2016 | 211 | 7 | St. Louis Blues | Filip Helt | LW | Litvinov Jr. | CZREP-JR. | CZE |