8 selections by the San Jose Sharks in the 2010 NHL Entry Draft.
| Year | Pick | Round | Team | Player | Pos | Amateur Club | League | Country |
|---|---|---|---|---|---|---|---|---|
| 2010 | 28 | 1 | San Jose Sharks | Charlie Coyle | C/RW | South Shore | EJHL | USA |
| 2010 | 88 | 3 | San Jose Sharks | Max Gaede | RW | Woodbury H.S. | HIGH-MN | USA |
| 2010 | 127 | 5 | San Jose Sharks | Cody Ferriero | C | Governor's Academy | HIGH-MA | USA |
| 2010 | 129 | 5 | San Jose Sharks | Freddie Hamilton | C | Niagara | OHL | CAN |
| 2010 | 136 | 5 | San Jose Sharks | Isaac MacLeod | D | Penticton | BCHL | CAN |
| 2010 | 163 | 6 | San Jose Sharks | Konrad Abeltshauser | D | Halifax | QMJHL | DEU |
| 2010 | 188 | 7 | San Jose Sharks | Lee Moffie | D | U. of Michigan | CCHA | USA |
| 2010 | 200 | 7 | San Jose Sharks | Christopher Crane | RW | Green Bay | USHL | USA |