6 selections by the San Jose Sharks in the 2006 NHL Entry Draft.
| Year | Pick | Round | Team | Player | Pos | Amateur Club | League | Country |
|---|---|---|---|---|---|---|---|---|
| 2006 | 16 | 1 | San Jose Sharks | Ty Wishart | D | Prince George | WHL | CAN |
| 2006 | 36 | 2 | San Jose Sharks | Jamie McGinn | LW | Ottawa | OHL | CAN |
| 2006 | 98 | 4 | San Jose Sharks | James Delory | D | Oshawa | OHL | CAN |
| 2006 | 143 | 5 | San Jose Sharks | Ashton Rome | RW | Kamloops | WHL | CAN |
| 2006 | 202 | 7 | San Jose Sharks | John McCarthy | LW | Boston University | H-EAST | USA |
| 2006 | 203 | 7 | San Jose Sharks | Jay Barriball | F | Sioux Falls | USHL | USA |