8 selections by the Philadelphia Flyers in the 2000 NHL Entry Draft.
| Year | Pick | Round | Team | Player | Pos | Amateur Club | League | Country |
|---|---|---|---|---|---|---|---|---|
| 2000 | 28 | 1 | Philadelphia Flyers | Justin Williams | RW | Plymouth | OHL | CAN |
| 2000 | 94 | 3 | Philadelphia Flyers | Alexander Drozdetsky | F | SKA St. Petersburg | — | RUS |
| 2000 | 171 | 6 | Philadelphia Flyers | Roman Cechmanek | G | Vsetin | CZE | CZE |
| 2000 | 195 | 6 | Philadelphia Flyers | Colin Shields | RW | Cleveland | NAHL | GBR |
| 2000 | 210 | 7 | Philadelphia Flyers | John Eichelberger | C | Green Bay | USHL | USA |
| 2000 | 227 | 7 | Philadelphia Flyers | Guillaume Lefebvre | C | Rouyn-Noranda | QMJHL | CAN |
| 2000 | 259 | 8 | Philadelphia Flyers | Regan Kelly | D | Nipawin | — | CAN |
| 2000 | 287 | 9 | Philadelphia Flyers | Milan Kopecky | LW | Slavia Praha Jr. | Czech | CZE |