8 selections by the Columbus Blue Jackets in the 2010 NHL Entry Draft.
| Year | Pick | Round | Team | Player | Pos | Amateur Club | League | Country |
|---|---|---|---|---|---|---|---|---|
| 2010 | 4 | 1 | Columbus Blue Jackets | Ryan Johansen | C | Portland | WHL | CAN |
| 2010 | 34 | 2 | Columbus Blue Jackets | Dalton Smith | LW | Ottawa | OHL | CAN |
| 2010 | 55 | 2 | Columbus Blue Jackets | Petr Straka | RW | Rimouski | QMJHL | CZE |
| 2010 | 94 | 4 | Columbus Blue Jackets | Brandon Archibald | D | Sault Ste. Marie | OHL | USA |
| 2010 | 102 | 4 | Columbus Blue Jackets | Mathieu Corbeil | G | Halifax | QMJHL | CAN |
| 2010 | 124 | 5 | Columbus Blue Jackets | Austin Madaisky | D | Kamloops | WHL | CAN |
| 2010 | 154 | 6 | Columbus Blue Jackets | Dalton Prout | D | Barrie | OHL | CAN |
| 2010 | 184 | 7 | Columbus Blue Jackets | Martin Ouellette | G | Kimball Union Academy | HIGH-NH | CAN |