10 selections by the Columbus Blue Jackets in the 2006 NHL Entry Draft.
| Year | Pick | Round | Team | Player | Pos | Amateur Club | League | Country |
|---|---|---|---|---|---|---|---|---|
| 2006 | 6 | 1 | Columbus Blue Jackets | Derick Brassard | C | Drummondville | QMJHL | CAN |
| 2006 | 69 | 3 | Columbus Blue Jackets | Steve Mason | G | London | OHL | CAN |
| 2006 | 85 | 3 | Columbus Blue Jackets | Tom Sestito | LW | Plymouth | OHL | USA |
| 2006 | 113 | 4 | Columbus Blue Jackets | Ben Wright | D | Lethbridge | WHL | CAN |
| 2006 | 129 | 5 | Columbus Blue Jackets | Robert Nyholm | RW | IFK Jr. | Finland Jr. | FIN |
| 2006 | 136 | 5 | Columbus Blue Jackets | Nick Sucharski | LW | Michigan State U. | CCHA | CAN |
| 2006 | 142 | 5 | Columbus Blue Jackets | Maxime Frechette | D | Drummondville | QMJHL | CAN |
| 2006 | 159 | 6 | Columbus Blue Jackets | Jesse Dudas | D | Prince George | WHL | CAN |
| 2006 | 189 | 7 | Columbus Blue Jackets | Derek Dorsett | RW | Medicine Hat | WHL | CAN |
| 2006 | 194 | 7 | Columbus Blue Jackets | Matt Marquardt | LW | Moncton | QMJHL | CAN |