6 selections by the Florida Panthers in the 2021 NHL Entry Draft.
| Year | Pick | Round | Team | Player | Pos | Amateur Club | League | Country |
|---|---|---|---|---|---|---|---|---|
| 2021 | 24 | 1 | Florida Panthers | Mackie Samoskevich | RW | Chicago | USHL | USA |
| 2021 | 56 | 2 | Florida Panthers | Evan Nause | D | Quebec | QMJHL | CAN |
| 2021 | 120 | 4 | Florida Panthers | Vladislav Lukashevich | D | Yaroslavl 2 | RUSSIA-JR. | RUS |
| 2021 | 152 | 5 | Florida Panthers | Kirill Gerasimyuk | G | SKA-Varyagi | RUSSIA-JR. | RUS |
| 2021 | 184 | 6 | Florida Panthers | Jakub Kos | LW | Ilves Jr. | FINLAND-JR. | CZE |
| 2021 | 210 | 7 | Florida Panthers | Braden Hache | D | Kingston | OHL | USA |