8 selections by the Calgary Flames in the 2021 NHL Entry Draft.
| Year | Pick | Round | Team | Player | Pos | Amateur Club | League | Country |
|---|---|---|---|---|---|---|---|---|
| 2021 | 13 | 1 | Calgary Flames | Matt Coronato | RW | Chicago | USHL | USA |
| 2021 | 45 | 2 | Calgary Flames | William Stromgren | LW | Modo | SWEDEN-2 | SWE |
| 2021 | 77 | 3 | Calgary Flames | Cole Huckins | C | Acadie-Bathurst | QMJHL | CAN |
| 2021 | 89 | 3 | Calgary Flames | Cameron Whynot | D | Halifax | QMJHL | CAN |
| 2021 | 141 | 5 | Calgary Flames | Cole Jordan | D | Moose Jaw | WHL | CAN |
| 2021 | 168 | 6 | Calgary Flames | Jack Beck | RW | Ottawa | OHL | CAN |
| 2021 | 173 | 6 | Calgary Flames | Lucas Ciona | LW | Seattle | WHL | CAN |
| 2021 | 205 | 7 | Calgary Flames | Arsenii Sergeev | G | Shreveport | NAHL | RUS |