8 selections by the Boston Bruins in the 2010 NHL Entry Draft.
| Year | Pick | Round | Team | Player | Pos | Amateur Club | League | Country |
|---|---|---|---|---|---|---|---|---|
| 2010 | 2 | 1 | Boston Bruins | Tyler Seguin | C | Plymouth | OHL | CAN |
| 2010 | 32 | 2 | Boston Bruins | Jared Knight | C | London | OHL | USA |
| 2010 | 45 | 2 | Boston Bruins | Ryan Spooner | C | Peterborough | OHL | CAN |
| 2010 | 97 | 4 | Boston Bruins | Craig Cunningham | LW | Vancouver | WHL | CAN |
| 2010 | 135 | 5 | Boston Bruins | Justin Florek | LW | Northern Michigan U. | CCHA | USA |
| 2010 | 165 | 6 | Boston Bruins | Zane McIntyre | G | Thief River Falls | HIGH-MN | USA |
| 2010 | 195 | 7 | Boston Bruins | Maxim Chudinov | D | Cherepovets | RUSSIA | RUS |
| 2010 | 210 | 7 | Boston Bruins | Zach Trotman | D | Lake Superior | CCHA | USA |