Buffalo Sabres 1978 Draft Picks9 selections by the Buffalo Sabres in the 1978 NHL Entry Draft.
| Year | Pick | Round | Team | Player | Pos | Amateur Club | League | Country |
|---|---|---|---|---|---|---|---|---|
| 1978 | 13 | 1 | Buffalo Sabres | Larry Playfair | D | Portland Winter Hawks | WCHL | CAN |
| 1978 | 32 | 2 | Buffalo Sabres | Tony McKegney | LW | Kingston Canadians | OHA | CAN |
| 1978 | 49 | 3 | Buffalo Sabres | Rob McClanahan | C | U. of Minnesota | NCAA | USA |
| 1978 | 66 | 4 | Buffalo Sabres | — | — | Sudbury Wolves | OHA | — |
| 1978 | 82 | 5 | Buffalo Sabres | Randy Ireland | G | Flint Generals | IHL | CAN |
| 1978 | 99 | 6 | Buffalo Sabres | Cameron Macgregor | LW | Cornwall Royals | QMJHL | CAN |
| 1978 | 116 | 7 | Buffalo Sabres | — | — | Saginaw Gears | IHL | — |
| 1978 | 133 | 8 | Buffalo Sabres | Eric Strobel | C | U. of Minnesota | NCAA | USA |
| 1978 | 150 | 9 | Buffalo Sabres | Eugene O'Sullivan | C | Calgary Wranglers | WCHL | CAN |